ProFunc helps identify the likely biochemical function of a protein from its three-dimensional structure. It uses both sequence- and structure-based methods to try to provide clues as the the protein’s likely or possible function. Often, where one method fails to provide any functional insight another may be more helpful.
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ProFunc: a server for predicting protein function from 3D structure.
Laskowski RA, Watson JD, Thornton JM.
Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W89-93.