Jan 242013
 

ProDGe 20110509

:: DESCRIPTION

ProDGe (Protein Domain Gene) visualizes existing and suggests novel domaindomain interactions and protein-protein interactions at the domain level. The comprehensive dataset behind ProDGe consists of protein, domain and interaction information for both layers, collected and combined appropriately from UniProt, Pfam, DOMINE and IntAct. Based on known domain interactions, ProDGe suggests novel protein interactions and assigns them to four confidence classes, depending on the reliability of the underlying domain interaction. Furthermore, ProDGe is able to identify potential homologous interaction partners in other species, which is particularly helpful when investigating poorly annotated species.

::DEVELOPER

the Center for Bioinformatics Tübingen (Zentrum für Bioinformatik Tübingen, ZBIT).

:: SCREENSHOTS

ProDGe

:: REQUIREMENTS

  • Linux/ WIndows/MacOsX
  • Java

:: DOWNLOAD

  ProDGe

:: MORE INFORMATION

Citation

Büchel, Finja, Wrzodek, Clemens, Mittag, Florian, Dr?ger, Andreas, Schr?der, Adrian, and Zell, Andreas.
ProDGe: investigating protein-protein interactions at the domain level.
Nature Precedings (2011)

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