Mar 132011
 

primeGEM 0.2

:: DESCRIPTION

primeGEM is a program that performs probabilistic orthology analysis (Arvestad et al. 2003, 2004, submitted, Sennblad and Lagergren, 2009). It computes for a pair of genes the probability that they are orthologous (note that this correpsponds to the probability that their least common ancestor is a speciation). It is based on the gene evolution model which models gene duplication and loss using a generalized birth-death model with threee parameters. The parameters can be integrated over using MCMC or (soon) maximized over using ML.

::DEVELOPER

Stockholm Bioinformatics Center

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / MacOsX

:: DOWNLOAD

primeGEM

:: MORE INFORMATION

Citation:

Sennblad, Lagergren, 2009, Probabilistic orthology analysis, Systematic Biology (2009) 58 (4): 411-424.

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