polyadq is a program for detection of human polyadenylation signals. To avoid training on possibly flawed data, the development of polyadq began with a de novo characterization of human mRNA 3′ processing signals. This information was used in training two quadratic discriminant functions that polyadq uses to evaluate potential polyA signals.
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Gene. 1999 Apr 29;231(1-2):77-86.
Detection of polyadenylation signals in human DNA sequences.
Tabaska JE, Zhang MQ.