Aug 252013
 

PhyloCon v3b

:: DESCRIPTION

PhyloCon (Phylogenetic Consensus) combines phylogenetic data with coregulated genes to identify regulatory motifs. PhyloCon is a motif discovery program. It is derived from a well established program “Consensus”, with comparative genomic features added.  PhyloCon assumes a “multiple gene, multiple species” model. It takes into account both conservation among orthologous genes and co-regulation of genes within a species. This algorithm first aligns conserved regions of orthologous sequences into multiple sequence alignments, or profiles, then compares profiles representing non-orthologous sequences. Motifs emerge as common regions in these profiles. The program will determine the width of the pattern being sought.

::DEVELOPER

Stormo Lab in Department of Genetics, Washington University

:: SCREENSHOTS

N/A

:: REQUIREMENTS

:: DOWNLOAD

 PhyloCon

:: MORE INFORMATION

Citation

Bioinformatics. 2003 Dec 12;19(18):2369-80.
Combining phylogenetic data with co-regulated genes to identify regulatory motifs.
Wang T, Stormo GD.

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