Phylo 3.3.2 / Open-Phylo – Gaming Framework to Align Genomic Data

Phylo 3.3.2 / Open-Phylo


Phylo is a human-based computing framework applying “crowd sourcing” techniques to solve the Multiple Sequence Alignment (MSA) problem. The key idea of Phylo is to convert the MSA problem into a casual game that can be played by ordinary web users with a minimal prior knowledge of the biological context.

Open-Phylo is an open crowd-computing platform to solve the multiple sequence alignment problem.


Computer Science and Biology at McGill




  • Web browser


Phylo ; for iSO; for Android



Genome Biol. 2013;14(10):R116.
Open-Phylo: a customizable crowd-computing platform for multiple sequence alignment.
Kwak D, Kam A, Becerra D, Zhou Q, Hops A, Zarour E, Kam A, Sarmenta L, Blanchette M, Waldispühl J.

PLoS One. 2012;7(3):e31362. doi: 10.1371/journal.pone.0031362. Epub 2012 Mar 7.
Phylo: a citizen science approach for improving multiple sequence alignment.
Kawrykow A1, Roumanis G, Kam A, Kwak D, Leung C, Wu C, Zarour E; Phylo players, Sarmenta L, Blanchette M, Waldispühl J.