PhenoPred is a web-based tool designed to detect novel gene-disease associations in humans. It is based on known gene-disease associations, protein-protein interaction data, protein functional annotation at a molecular level and protein sequence data. Machine learning principles are used to integrate heterogeneous data sources. PhenoPred can be used to prioritize genes based on their likelihood to be associated with a given disease or to prioritize diseases for a given query gene.
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Proteins. 2008 Aug 15;72(3):1030-7. doi: 10.1002/prot.21989.
An integrated approach to inferring gene-disease associations in humans.
Radivojac P1, Peng K, Clark WT, Peters BJ, Mohan A, Boyle SM, Mooney SD.