PhenoFam performs gene set enrichment analysis by employing structural and functional information on families of protein domains as annotation terms. The tool is designed to analyse complete sets of results from quantitative high-throughput studies (gene expression microarrays, functional RNAi screens, etc.) without prior pre-filtering or hits-selection steps.
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BMC Bioinformatics. 2010 May 17;11:254. doi: 10.1186/1471-2105-11-254.
PhenoFam – gene set enrichment analysis through protein structural information.
Paszkowski-Rogacz M, Slabicki M, Pisabarro MT, Buchholz F.