The PERT algorithm is designed for expression deconvolution of samples of mixed cell types, where the expression profiles of most of the individual cell types are available and we simply want to estimate the proportion of each mixed sample that is attributable to each individual cell type.
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PLoS Comput Biol. 2012;8(12):e1002838. doi: 10.1371/journal.pcbi.1002838. Epub 2012 Dec 20.
PERT: a method for expression deconvolution of human blood samples from varied microenvironmental and developmental conditions.
Qiao W1, Quon G, Csaszar E, Yu M, Morris Q, Zandstra PW.