PEDEL (Programme for Estimating Diversity in Error-prone PCR Libraries) can be used to calculate the expected number of distinct variants present in a library, given the library size, mean substitution rate and parent sequence length. On the web page, the user may produce plots of the expected number of distinct daughter sequences as a function of library size and substitution rate.
- Linux / Windows / MacOsX
- C++ Compiler
:: MORE INFORMATION
AndrewE. Firth, Wayne M. Patrick, 2005,
Statistics of protein library construction,
Bioinformatics, 21, 3314-3315.