The PDT (Pedigree Disequilibrium Test)analysis program allows the user to evaluate evidence of linkage disequilibrium (LD) in general pedigree data. All family data may be used without nullifying the validity of the association test, even when there is more than one affected in a family. The PDT program performs both allele-specific and genotype-specific LD analysis of individual markers. Version 5.1 adds the ability to perform genotype-specific analysis over marker sets.Â
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Eden R. Martin, S. Monks, L. Warren, N. Kaplan (2000)
A Test for Linkage and Association in General Pedigrees:The Pedigree Disequilibrium Test.
Am. J. Hum. Genet. 67:146-154, 2000