Pathicularis the Cytoscape plug-in which identifies path motifs in integrated networks and arranges them in a modular structure. After the integrated network and the source network (deletion or overexpression in this case) are loaded into Cytoscape, Pathicular can be used to find all the paths of a given type in the source network using the integrated network. A p-value is provided to check the overrepresentation of the path of interest.
:: MORE INFORMATION
Genome Biol. 2010;11(3):R32. Epub 2010 Mar 11.
Characterizing regulatory path motifs in integrated networks using perturbational data.
Joshi A, Van Parys T, Peer YV, Michoel T.