BCRgt is a Bayesian Cluster Regression based genotyping approach to genotype samples with Copy Number Alterations (CNAs). This is motivated by the facts that cancer tissues often have large regions of genetic structural alterations such as CNAs, and that researchers have been interested in genotyping SNPs from such samples.
Zhide Fang, Ph.D., LSU Health Sciences Center
- R package
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BMC Bioinformatics. 2014 Mar 15;15:74. doi: 10.1186/1471-2105-15-74.
BCRgt: a Bayesian cluster regression-based genotyping algorithm for the samples with copy number alterations.
Yang S, Cui X, Fang Z1.