Sep 022013
 

p53scan 1.05 & p63scan

:: DESCRIPTION

p53scan is an algorithm to search for p53 consensus binding motif, as determined in a genome-wide ChIP-chip study, in DNA sequences. The same algorithm has also been combined with the p63 binding motif obtained from a genome-wide p63 ChIP-seq study in human keratinocytes to form p63scan.

::DEVELOPER

Nijmegen Center for Molecular Life Sciences 

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux/ Windows/ MacOsX
  • C Compiler
  • Python

:: DOWNLOAD

 p53scan

:: MORE INFORMATION

Citation

Nucleic Acids Res. 2008 Jun;36(11):3639-54. doi: 10.1093/nar/gkn232. Epub 2008 May 12.
Characterization of genome-wide p53-binding sites upon stress response.
Smeenk L, van Heeringen SJ, Koeppel M, van Driel MA, Bartels SJ, Akkers RC, Denissov S, Stunnenberg HG, Lohrum M.

Kouwenhoven EN, van Heeringen SJ, Tena JJ, Oti M, Dutilh BE et al.
Genome-wide profiling of p63 DNA-binding sites identifies an element that regulates gene expression during limb development in the 7q21 SHFM1 locus.
PLoS Genet. 2010 Aug 19;6(8):e1001065. doi: 10.1371/journal.pgen.1001065.

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