OncodriveCLUST is a method to identify genes in which mutations accumulate within specific regions of the protein, which denote events selected by the tumour. It computes a score measuring the mutation clustering of a gene across the protein sequence and compares it with a background model.
:: MORE INFORMATION
Tamborero D, Gonzalez-Perez A and Lopez-Bigas N
Oncodrive-CLUST: a method to reveal cancer drivers by evaluating their mutation clustering.
Manuscript in preparation