OncodriveCIS is a method to identify genes that accumulate copy number alterations important for tumour development. This is done by computing the functional impact of CNAs by measuring their effect on the expression of the genes affected.
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Tamborero D, Lopez-Bigas N and Gonzalez-Perez A.
Oncodrive-CIS: a method to reveal likely driver genes based on the impact of their copy number changes on expression.
PLoS ONE 8(2): e55489. doi:10.1371/journal.pone.0055489