OCTOPUS / SPOCTOPUS
OCTOPUS is a new method for predicting transmembrane protein topology is presented and benchmarked using a dataset of 124 sequences with known structures.
SPOCTOPUS is a method for combined prediction of signal peptides and membrane protein topology, suitable for genome-scale studies.
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Bioinformatics. 2008 Aug 1;24(15):1662-8. doi: 10.1093/bioinformatics/btn221. Epub 2008 May 12.
OCTOPUS: improving topology prediction by two-track ANN-based preference scores and an extended topological grammar.
Viklund H1, Elofsson A.
Bioinformatics. 2008 Dec 15;24(24):2928-9. doi: 10.1093/bioinformatics/btn550. Epub 2008 Oct 22.
SPOCTOPUS: a combined predictor of signal peptides and membrane protein topology.
Viklund H1, Bernsel A, Skwark M, Elofsson A.