NoDe (Noise Detector) is a new error correction algorithm which was trained to identify those positions in 454 sequencing reads that are likely to have an error, and subsequently clusters those error-prone reads with correct reads resulting in error-free representative read.
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NoDe: a fast error-correction algorithm for pyrosequencing amplicon reads.
Mysara M, Leys N, Raes J, Monsieurs P.
BMC Bioinformatics. 2015 Mar 15;16(1):88.