Mar 212011
 

NMFF

:: DESCRIPTION

NMFF (Normal Mode Flexible Fitting) is an evolving package of programs and methods that enable the flexible multi-resolution fitting of large atomically detailed structures into electron density maps from cryoEM, tomography and related lower resolution methods.The theory and methods behind NMFF are based on searching along a few lowest frequency normal mode vectors, constructed from a multi-resolution elastic network representation of the atomic structure of interest, to maximize the correlation between the computed electron density for the flexible model and the experimental density.

::DEVELOPER

NIH Research Resource Center for the Development of Multiscale Modeling Tools for Structural Biology

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / MacOsX

:: DOWNLOAD

NMFF

:: MORE INFORMATION

Citation

F Tama, O Miyashita and CL Brooks, III. Flexible multi-scale fitting of atomic structures into low-resolution electron density maps with elastic network normal mode analysis.
Journal of Molecular Biology, 2004, 337 (4), 985-99.

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