MVQueries is a software of classifying short gene expression time-courses. Short gene expression time-courses monitoring response to toxins are represented as piecewise constant functions, which are modeled as left–right Hidden Markov Models. Our software implements a Bayesian approach to parameter estimation and in inference. Compared to previously published work, we improve prediction accuracy by 7 and 4%, respectively, when classifying toxicology and stress response data and e also reduce running times by at least a factor of 140.
- Linux / Windows / MacOsX
:: MORE INFORMATION
Bioinformatics. 2011 Apr 1;27(7):946-52. Epub 2011 Jan 25.
Classifying short gene expression time-courses with Bayesian estimation of piecewise constant functions.
Hafemeister C, Costa IG, Sch?nhuth A, Schliep A.