Musket is an efficient multistage k-mer based corrector for Illumina short read data. This corrector employs the k-mer spectrum approach and introduces three correction techniques in a multistage workflow. Our performance evaluation results, in terms of correction quality and de novo genome assembly measures, reveal that Musket is consistently one of the top performing substitution-error-based correctors. In addition, Musket is multi-threaded using a master-slave model and demonstrates superior parallel scalability compared to all other evaluated correctors as well as a highly competitive overall execution time.
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Yongchao Liu, Jan Schroeder and Bertil Schmidt:
“ Musket: a multistage k-mer spectrum based error corrector for Illumina sequence data“.
Bioinformatics, 2013, 29(3): 308-315