MSstats is an R package that provides tools for protein quantification in label-free and label-based LC-MS experiments and also SRM experiments based on a family of linear mixed-effects models as the integration of MSstats and SRMstats.
Laboratory for Statistical Proteomics and Bioinformatics , Purdue University
- Linux/ MacOsX/ Windows
- R package
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Bioinformatics. 2014 May 2. [Epub ahead of print]
MSstats: an R package for statistical analysis of quantitative mass spectrometry-based proteomic experiments.
Choi M1, Chang CY, Clough T, Broudy D, Killeen T, Maclean B, Vitek O.
BMC Bioinformatics. 2012;13 Suppl 16:S6. doi: 10.1186/1471-2105-13-S16-S6. Epub 2012 Nov 5.
Statistical protein quantification and significance analysis in label-free LC-MS experiments with complex designs.
Clough T, Thaminy S, Ragg S, Aebersold R, Vitek O.