mSD – Regulatory Module Identification

mSD

:: DESCRIPTION

mSD (motif-guided sparse decomposition) identifies gene regulatory modules by integrating gene expression data and DNA sequence motif information. The mSD approach is implemented as a two-step algorithm comprising estimates of (1) transcription factor activity and (2) the strength of the predicted gene regulation event(s).

::DEVELOPER

Computational Bioinformatics & Bio-imaging Laboratory (CBIL)

:: SCREENSHOTS

N/A

:: REQUIREMENTS

:: DOWNLOAD

 mSD

:: MORE INFORMATION

Citation:

BMC Bioinformatics. 2011 Mar 22;12:82.
Motif-guided sparse decomposition of gene expression data for regulatory module identification.
Gong T, Xuan J, Chen L, Riggins RB, Li H, Hoffman EP, Clarke R, Wang Y.

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