Mar 042013
 

mRNA optimiser 1.0

:: DESCRIPTION

The mRNA optimiser is a tool that redesigns a gene messenger RNA to optimise its secondary structure, without affecting the polypeptide sequence. The tool can either maximize or minimize the molecule minimum free energy (MFE), thus resulting in decreased or increased secondary structure strength.

::DEVELOPER

UA.PT Bioinformatics

:: SCREENSHOTS

N/A

::REQUIREMENTS

  • Linux/ Windows/MacOsX
  • Java

:: DOWNLOAD

 mRNA optimiser

:: MORE INFORMATION

Citation

P. Gaspar, G. Moura, M. A. S. Santos, and J. L. Oliveira
mRNA secondary structure optimization using a correlated stem–loop prediction
Nucleic Acids Research, Jan 2013, doi: 10.1093/nar/gks1473

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