MRD (Mutation Region Detection) is a software package for finding mutation regions where the input individuals are closely related, but the pedigree is not given. MRD takes the genotype data on a chromosome as well as the disease status for a set of input individuals without any pedigree information and outputs the predicted mutation regions.
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J Bioinform Comput Biol. 2005 Oct;3(5):1039-52.
Randomized algorithms for motif detection.
Wang L, Dong L.