Mprobe is software to design optimal probes for oligonucleotide microarrays with the following new features. First, a paradox-based sequence database management system (SDMS) has been developed and integrated into the software, which can recognize the sequences in GenBank, EMBL, and FastA formats. Second, the threshold to reject the probes based on secondary structure was avoided.
Center of Computational Biology, Beijing Institute of Basic Medical Sciences
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Mprobe 2.0: computer-aided probe design for oligonucleotide microarray.
Li W, Ying X.
Appl Bioinformatics. 2006;5(3):181-6.