ModLink+ is a software to predict the fold of a target protein sequence. ModLink+includes an improved procedure for extrapolating links that iteratively varies the number of interactions required to consider a protein as a hub. This new algorithm, that comprises a ‘self-adaptive’ definition of hub proteins, has increased applicability without affecting its accuracy.
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Bioinformatics. 2009 Jun 15;25(12):1506-12. Epub 2009 Apr 8.
ModLink+: improving fold recognition by using protein-protein interactions.
Fornes O, Aragues R, Espadaler J, Marti-Renom MA, Sali A, Oliva B.