MicroMerge automates merging of microsatellite data sets that were genotyped at different facilities or using different protocols or platforms. The software employs a Bayesian statistical model that matches allele frequencies between data sets (Presson et al. 2006). MicroMerge v2.0 enables the following aspects of control: 1) output file formats which can be handled by most statistical genetic analysis packages, 2) tailoring the algorithm to different merging scenarios, such as data sets with very different sample sizes or multiple data sets, 3) merging small data sets when a reliable set of allele frequencies are available, and 4) improving the quantity and 5) quality of merged data.
Angela P. Presson (firstname.lastname@example.org), UCLA Human Genetics
- Windows / Linux
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Angela P Presson , Eric M Sobel , Paivi Pajukanta , Christopher Plaisier , Daniel E Weeks , Karolina Åberg and Jeanette C Papp (2008)
Merging microsatellite data: enhanced methodology and software to combine genotype data for linkage and association analysis
BMC Bioinformatics 2008, 9:317