The MHC2Pred is an SVM based method for prediction of promiscuous MHC class II binding peptides.The average accuracy of SVM based method for 42 alleles is ~80%. The performence of the method was poorer for few allele due to smaller size of dataset. The performence of the method was tested through 5-fold cross-validation.
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Methods Mol Biol. 2007;409:201-15.
Application of machine learning techniques in predicting MHC binders.
Lata S, Bhasin M, Raghava GP.