MeltDNA is a tool for DNA hybridization and melting thermodynamics prediction. MeltDNA considers all factors those determine thermodynamic values, such as base composition, NN parameters, salt dependency (Na+ , Mg++ ), internal mismatch, dangling ends , loops etc. To improve NN model based calculations it relies on fusion matrices and these matrices are extensible. Currently MeltDNA predicts ∆ G, ∆ H, ∆ S, Tm, Ta and Extinction coeﬃcient at 260 nm values.
- Windows / Linux / MacOSX
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