MEAP is an R package for large-scale exon array data analysis.It includes a novel algorithm (PM-BayesBG) to estimate sequence-based backgrounds that allows more reliable expression estimation than the existing background correction methods. MEAP also contains algorithms for generating robust expression estimates at exon, alternatively spliced variant and gene levels that facilitates the quantitative analysis of alternative spliced variants in the whole transcriptome.
- R Package
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Chen P, Lepikhova T, Hu YZ, Monni O and Hautaniemi S.
Comprehensive Exon Array Data Processing Method for Quantitative Analysis of Alternative Spliced Variants.
Nucleic Acids Research. 2011 Oct;39(18):e123. Epub 2011 Jul 10.