MCQTL software package is a software of performing QTL mapping in multi-cross designs. It allows the analysis of the usual populations derived from inbred lines and can link the families by assuming that the QTL locations are the same in all of them. Moreover, a diallel modelling of the QTL genotypic effect is allowed in multiple related families. The implemented model is a linear regression model in which the probabilities of QTL genotypes are derived from multiple marker data. A composite interval mapping and an iterative QTL mapping are implemented to deal with multiple QTL models. Marker cofactor selections by forward or backward stepwise method are implemented as well as computation of threshold test values by permutation.
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Marie-Françoise Jourjon, Sylvain Jasson, Jacques Marcel, Baba Ngom and Brigitte Mangin
MCQTL: multi-allelic QTL mapping in multi-cross design
Bioinformatics 2005, 21, 128-130