Mc-Sym (Macromolecular Conformations by SYMbolic programming) is a software that builds RNA 3-D structures using coordinates and relations between residues extracted from X-ray crystallography and NMR found in the RCSB Protein Data Bank and the Rutgers Nucleic Acid Database and from theoretical models. Constraints can be applied to the building procedure to ensure that the generated models are valid. The RNA structures properties and constraints are entered in a script or interactively within the mcsym interpreter.
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Robert Pinard, Dominic Lambert, Nils G. Walter, Joyce E. Heckman, François Major, and John M. Burke,
Structural Basis for the Guanosine Requirement of the Hairpin Ribozyme,
Biochemistry; 1999; 38(49); 16035-16039.