MBR (Microarray Blob Remover) is a microarray JAVA tool which allows rapid visualization, detection, and removalof blob-like defects as an initial quality control step. The software allows rapid visualization, detection, and removal of blob defects of a variety of sizes and shapes from different types of microarrays using their .CEL files. Removal of the affected probes in the blob-defects using MBR was shown to significantly improve sensitivity and FDR compared to leaving the affected probes in the analysis.
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Song JS, Maghsoudi K, Li W, Fox E, Quackenbush J, Shirley Liu X.
Microarray blob-defect removal improves array analysis.
Bioinformatics. 2007 Apr 15;23(8):966-71. Epub 2007 Mar 1.