MaxAlike 1.0 – Phylogenetic Reconstruction of incomplete Sequences by Maximum Likelihood

MaxAlike 1.0

:: DESCRIPTION

MaxAlike algorithm aims at reconstructing a nucleotide sequence in a target species, based on a multiple sequence alignment and a phylogenetic tree of homologous sequences from other species. For each alignment position the probabilities of occurrence for each nucleotide are computed, considering the phylogenetic position of the target species in the tree.

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::DEVELOPER

Center for non-coding RNA in Technology and Health (RTH)

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 MaxAlike

:: MORE INFORMATION

Citation:

P. Menzel, P. F. Stadler and J. Gorodkin:
maxAlike: Maximum-likelihood based sequence reconstruction with application to improved primer design for unknown sequences,
Bioinformatics, 2011, 27, 317-325.

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