MANTRA (Mode of Action by NeTwoRk Analysis) is a computational tool for the analysis of the Mode of Action (MoA) of novel drugs and the identification of known and approved candidates for ‚Äúdrug repositioning‚ÄĚ. It is based on network theory and non-parametric statistics on gene expression data.
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Bioinformatics. 2014 Feb 25. [Epub ahead of print]
Mantra 2.0: an online collaborative resource for drug mode of action and repurposing by network analysis.
Carrella D, Napolitano F, Rispoli R, Miglietta M, Carissimo A, Cutillo L, Sirci F, Gregoretti F, Di Bernardo D.