MAGIC is an integrative and accurate method for comparative genome mapping.The method consists of two phases: preprocessing for identifying “maximal similar segments,” and mapping for clustering and classifying these segments. MAGIC’s main novelty lies in its biologically intuitive clustering approach, which aims towards both calculating reorder-free segments and identifying orthologous segments. MAGIC can be used for identifying orthologous segments, analyzing duplications events, studying rearrangements, locating potential horizontal transfer events, etc.
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Swidan, F., Rocha, E. P. C., Shmoish, M., Pinter, R. Y.
An Integrative Method for Accurate Comparative Genome Mapping.
Comparative Genome Mapping. PLoS Comput Biol 2(8): e75.