LocNES (Locating Nuclear Export Signals or NESs) is a Support Vector Machine (SVM) predictor that locates classical nuclear export signals (NESs) in CRM1 cargoes. Export-Karyopherinβ CRM1 recognizes hundreds of broadly functioning proteins. Most CRM1 cargoes contain the classical NES (also known as leucine-rich NESs), a peptide with 8-15 amino acids, regularly spaced with conserved hydrophobic residues.
Chook Lab,UT Southwestern Medical Center
- Web Browser
:: MORE INFORMATION
LocNES: A computational tool for locating classical NESs in CRM1 cargo proteins.
Xu D, Marquis K, Pei J, Fu SC, Cağatay T, Grishin NV, Chook YM.
Bioinformatics. 2014 Dec 15. pii: btu826.