Mar 152014
 

Lever 2.0

:: DESCRIPTION

Lever systematically maps DNA regulatory motifs or motif combinations to the sets of genes that they likely regulate. Lever accomplishes this by assessing whether the motifs are enriched within cis regulatory modules (CRMs), predicted by our PhylCRM algorithm, in the noncoding sequences surrounding genes in a collection of gene sets.

::DEVELOPER

The Bulyk Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 Lever

:: MORE INFORMATION

Citation

Bioinformatics. 2012 Jun 1;28(11):1446-54. doi: 10.1093/bioinformatics/bts155. Epub 2012 Apr 5.
LOESS correction for length variation in gene set-based genomic sequence analysis.
Aboukhalil A, Bulyk ML.

Nat Methods. 2008 Apr;5(4):347-53. doi: 10.1038/nmeth.1188. Epub 2008 Mar 2.
Systematic identification of mammalian regulatory motifs’ target genes and functions.
Warner JB, Philippakis AA, Jaeger SA, He FS, Lin J, Bulyk ML.

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