LDSO (Linkage Disequilibrium with Several Options) is a completely self-contained program written in Fortran90. It is a complete computer program for simulations of whole diploid population histories under various historical scenarios based on the gene-dropping method (MacCluer et al. 1986). The random number generator from L’Ecuyer (1996) was used. The genetic history of one or two populations can be simulated; the output files can deliver various statistics (inbreeding rates, allele frequencies, linkage disequilibrium) on these populations for generations wished by the user. Evolutionary forces that are classically found in livestock populations, such as mutation, selection, changes in the population size or random drift, can be taken into account.
F. Ytournel(contact author)
- Linux / Windows
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J Anim Breed Genet. 2012 Oct;129(5):417-21. doi: 10.1111/j.1439-0388.2011.00986.x. Epub 2012 Jan 23.
LDSO: a program to simulate pedigrees and molecular information under various evolutionary forces.
Ytournel F, Teyssèdre S, Roldan D, Erbe M, Simianer H, Boichard D, Gilbert H, Druet T, Legarra A.