LBL 1.0 / LBLGXE 1.1 – Bayesian Lasso for detecting Rare Haplotype-Environment Interaction

LBL 1.0 / LBLGXE 1.1

:: DESCRIPTION

LBL (Logistic Bayesian Lasso) is an R package that performs Logistic Bayesian Lasso for finding association of SNP haplotypes with a trait in a case-control setting. Bayesian lasso is used to find the posterior distributions of logistic regression coefficients, which are then used to calculate Bayes Factor to test for association with haplotypes.

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LBLGXE expands on the original LBL. Gene-environment interaction (GXE)

::DEVELOPER

Statistical Genetics and Bioinformatics Group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

:: DOWNLOAD

 LBL / LBLGXE

:: MORE INFORMATION

Citation

Genet Epidemiol. 2014 Jan;38(1):31-41. doi: 10.1002/gepi.21773. Epub 2013 Nov 23.
Detecting rare haplotype-environment interaction with logistic Bayesian LASSO.
Biswas S1, Xia S, Lin S.

Biswas S, and Lin, S. (2011)
Logistic Bayesian Lasso for identifying association with rare haplotyp es and application to age-related macular degeneration.
Biometrics. 2011 Sep 28. doi: 10.1111/j.1541-0420.

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