KL-Rare is for performing four tests based on Kullback-Leeibler divergence to assess overall association of a group of common and rare variants with a common disease.
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Ann Hum Genet, 79 (3), 199-208 May 2015
Kullback-Leibler Distance Methods for Detecting Disease Association With Rare Variants From Sequencing Data
Asuman S Turkmen 1, Zhifei Yan, Yue-Qing Hu, Shili Lin