iWRAP is a threading program for identifying the putative interface between two protein sequences. iWRAP is based on RAPTOR, which is a single domain threading program. iWRAP considers only the interface of the template to predict interacting residues in a pair of query sequences. iWRAP uses the open-source optimization library (COIN-OR) to minimize the threading energy function.
Raghavendra Hosur (firstname.lastname@example.org)
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J Mol Biol. 2011 Feb 4;405(5):1295-310. doi: 10.1016/j.jmb.2010.11.025.
iWRAP: An interface threading approach with application to prediction of cancer-related protein-protein interactions.
Hosur R, Xu J, Bienkowska J, Berger B.