ISOpure 1.0 / ISOpureR 1.0.18 – Gene Expression Deconvolution and Purification

ISOpure 1.0 / ISOpureR 1.0.18

:: DESCRIPTION

ISOpure uses a set of tumor expression profiles and a panel of healthy tissue expression profiles to generate a purified cancer profile for each tumor sample, and an estimate of the proportion of RNA originating from cancerous cells.

ISOpureR: Deconvolution of Tumour Profiles

::DEVELOPER

QUON-TITATIVE BIOLOGY LABthe Boutros Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / MacOsX / Windows
  • MatLab / R

:: DOWNLOAD

 ISOpure , ISOpureR

:: MORE INFORMATION

Citation

BMC Bioinformatics. 2015 May 14;16:156. doi: 10.1186/s12859-015-0597-x.
ISOpureR: an R implementation of a computational purification algorithm of mixed tumour profiles.
Anghel CV, Quon G, Haider S, Nguyen F, Deshwar AG, Morris QD, Boutros PC

Genome Med. 2013 Mar 28;5(3):29.
Computational purification of individual tumor gene expression profiles leads to significant improvements in prognostic prediction.
Quon G, Haider S, Deshwar AG, Cui A, Boutros PC, Morris Q.