IBRENA (Insilico Biochemical REaction Network Analysis) is a software to aid the analysis of complex biological reaction networks. In order to reduce computation time, in some cases, ordinary differential equations (ODEs) are solved using Visual FORTRAN (HP-Compaq V6.6, Palo Alto, CA) with integrated IMSL library (Visual Numerics Inc., Houston, TX). This reduces the computational time required for time-consuming sensitivity analysis.
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Liu, G. and S. Neelamegham,
In silico Biochemical Reaction Network Analysis (IBRENA): a package for simulation and analysis of reaction networks.
Bioinformatics (2008) 24 (8): 1109-1111.