Hipsec is a tool for predicting high-level protein production in Aspergillus niger. The software predicts if gene overexpression of an extracellular protein will lead to successful high-level production in Aspergillus niger. The prediction is based on a protein’s amino acid sequence. One or more protein sequences can be pasted into the the text area (fasta format) or uploaded as a fasta file.
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Exploring Sequence Characteristics Related to High-Level Production of Secreted Proteins in Aspergillus niger.
van den Berg BA, Reinders MJ, Hulsman M, Wu L, Pel HJ, Roubos JA, de Ridder D.
PLoS One. 2012;7(10):e45869. doi: 10.1371/journal.pone.0045869. Epub 2012 Oct 1.