GRIL is a tool that can be used to identify the location of rearrangements and inversions in the backbone of a set of DNA sequences. GRIL works by identifying exactly matching regions present in all sequences under consideration and organizing them into groups of collinear regions. GRIL removes small regions of collinearity that appear unlikely to be true sequence rearrangements based on user-specified criteria such as the length of the collinear region and the percent sequence identity of the collinear region. The size of sequences that GRIL can be applied to is dependent on the amount of available memory.
- Linux/ Windows
:: MORE INFORMATION
Aaron E. Darling, Bob Mau, Frederick R. Blattner and Nicole T. Perna
GRIL: genome rearrangement and inversion locator
Bioinformatics (2004) 20 (1): 122-124.