GRASP is a gene annotation tool for metagenomic studies. GRASP assembles the fragmented short-peptides, which are called from the NGS reads, and aligns the assembled contigs to the query reference protein. GRASP achieves much higher sensitivity than BLASTP for gene annotation purpose.
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GRASP: Guided Reference-based Assembly of Short Peptides.
Zhong C, Yang Y, Yooseph S.
Nucleic Acids Res. 2014 Nov 20. pii: gku1210