May 282014
 

GRAIL / VIZ-GRAIL

:: DESCRIPTION

GRAIL is a tool to examine relationships between genes in different disease associated loci. Given several genomic regions or SNPs associated with a particular phenotype or disease, GRAIL looks for similarities in the published scientific text among the associated genes.

GRAIL Online Version

The VIZ-GRAIL software allows users to create informative circle plots of genetic loci that visualizes the functional similarites between genes in an intuitive manner. Code that interact with the online site is available here for download. VIZ-grail is implemented as two separate perl scripts.

::DEVELOPER

The Raychaudhuri Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Mac OsX / Windows
  • Perl

:: DOWNLOAD

 VIZ-GRAIL

:: MORE INFORMATION

Citation

Bioinformatics. 2011 Jun 1;27(11):1589-90. doi: 10.1093/bioinformatics/btr185.
VIZ-GRAIL: visualizing functional connections across disease loci.
Raychaudhuri S.

Raychaudhuri, S., Plenge, R.M., Rossin, E.J., Ng, A.C.Y., International Schizophrenia Consortium, Purcell, S.M., Sklar, P., Scolnick, E.M., Xavier, R.J., Altshuler, D., and Daly, M.J.
Identifying Relationships Among Genomic Disease Regions: Predicting Genes at Pathogenic SNP Associations and Rare Deletions.
PLOS Genetics, 2009. 5(6):e1000534.

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