The current GPCR-GIA is a 2-layer predictor: the 1st layer prediction engine is for identifying a query protein sequence as GPCR on non-GPCR
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Protein Eng Des Sel. 2009 Nov;22(11):699-705. doi: 10.1093/protein/gzp057. Epub 2009 Sep 22.
GPCR-GIA: a web-server for identifying G-protein coupled receptors and their families with grey incidence analysis.
Lin WZ1, Xiao X, Chou KC.